Publication entry:

Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants

Full citation: Iqbal, S., Pérez-Palma, E., Jespersen, J. B., May, P., Hoksza, D., Heyne, H. O., Ahmed, S. S., Rifat, Z. T., Rahman, M. S., Lage, K., et al. (2020). Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants. Proceedings of the National Academy of Sciences, 117(45), 28201–28211.
BibTeX citation file download: iqbal2020comprehensive.bib

Internal authors

David Hoksza

Head of department, Associate professor

Research topics

Bioinformatics

Bioinformatics sits on the interface of computer science and molecular biology where it helps to manage, understand and analyze biological and biomedical data. Our research in bioinformatics focuses on the development of software tools applicable mainly in the domain of structural bioinformatics and visualization. These include tools for protein binding site detection, with the application in computational drug discovery, or tools for visualization of the structure of macromolecules. All our methods are implemented as software solutions used by thousands of users all over the world. Most of our tools were first implemented as bachelor or master thesis in our department.